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Alternative splicing linked to mammal lifespan — Level A1 — white mouse lot toy

Alternative splicing linked to mammal lifespanCEFR A1

24 Nov 2025

Adapted from Iqbal Pittalwala - UC Riverside, Futurity CC BY 4.0

Photo by James Wainscoat, Unsplash

Level A1 – Beginner
2 min
71 words
  • Researchers published a new study in Nature Communications journal.
  • They study alternative splicing in mammals.
  • They compare 26 different mammal species.
  • The species live from 2.2 to 37 years.
  • Alternative splicing makes many different proteins.
  • Splicing predicts lifespan better than gene activity.
  • They also study six tissues, including the brain.
  • The brain shows twice as many events.
  • Many RNA-binding proteins control splicing.
  • The work finds new targets for healthy aging.

Difficult words

  • animalA living thing that can move and feel.
    animals
  • studyA careful examination or investigation.
  • mammalA type of animal that has hair and feeds with milk.
    mammal types
  • geneA part of DNA that controls traits.
    genes
  • spliceTo join or connect parts together.
    spliced, splicing
  • brainThe organ in the head that controls thinking.
  • agingThe process of becoming older.

Tip: hover, focus or tap highlighted words in the article to see quick definitions while you read or listen.

Discussion questions

  • What animals do you think live the longest?
  • Why do you think studying genes is important?
  • How do you feel about aging?

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