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Tofersen slows a rare form of ALS (Level A1) — two white tablets

Tofersen slows a rare form of ALSCEFR A1

26 Dec 2025

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Adapted from Washington U. in St. Louis, Futurity • CC BY 4.0

Photo by Thought Catalog, Unsplash

Level A1 – Beginner
2 min
66 words
  • ALS is a disease that stops the nerves for movement.
  • It also makes breathing harder over time.
  • Tofersen is a medicine for a rare form of ALS.
  • The medicine can slow how fast ALS gets worse.
  • Some people stay the same or get better.
  • Improvements included better hand grip and breathing.
  • Some people had headaches or body pain.
  • Researchers are still studying the medicine and results.

Difficult words

  • disease — A health problem that makes the body worse
  • nerve — A body part that sends messages to muscles
    nerves
  • breathe — To take air into the lungs and out
    breathing
  • medicine — A drug or treatment that helps a sick person
  • rare — Not common; only a few cases
  • improvement — A change that makes the condition better
    Improvements

Tip: hover, focus or tap highlighted words in the article to see quick definitions while you read or listen.

Discussion questions

  • Do you know anyone with a long illness?
  • Have you ever had a headache or body pain?
  • Do you take medicine when you are sick?

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