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New method builds synthetic phage genomes — Level A1 — a close up of a flower with a blurry background

New method builds synthetic phage genomesCEFR A1

6 Dec 2025

Adapted from U. Pittsburgh, Futurity CC BY 4.0

Photo by Mike B, Unsplash

Level A1 – Beginner
2 min
72 words
  • Researchers developed a new way to build phage DNA.
  • The method makes fully synthetic phage genomes possible.
  • Scientists can now add or remove single genes.
  • This work may help treat bacterial infections.
  • Some phage DNA is hard to make in the lab.
  • DNA carries genetic instructions for the phage.
  • The new process solves problems with hard DNA.
  • Scientists make genomes in parts and join them.
  • This may speed finding the right phage.

Difficult words

  • phagea tiny virus that attacks bacteria
  • genomeall the genetic instructions of a living thing
    genomes
  • genea small part of genetic material giving instructions
    genes
  • syntheticmade by people, not made by nature
  • bacterialrelated to bacteria, small living cells
  • infectionwhen bacteria or other germs cause illness
    infections

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Discussion questions

  • Have you heard the word phage before?
  • Do you know what DNA does?
  • Would you like to learn more about genes?

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