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New method builds synthetic phage genomes — Level A1 — a close up of a flower with a blurry background

New method builds synthetic phage genomesCEFR A1

6 Dec 2025

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Adapted from U. Pittsburgh, Futurity • CC BY 4.0

Photo by Mike B, Unsplash

Level A1 – Beginner
2 min
72 words
  • Researchers developed a new way to build phage DNA.
  • The method makes fully synthetic phage genomes possible.
  • Scientists can now add or remove single genes.
  • This work may help treat bacterial infections.
  • Some phage DNA is hard to make in the lab.
  • DNA carries genetic instructions for the phage.
  • The new process solves problems with hard DNA.
  • Scientists make genomes in parts and join them.
  • This may speed finding the right phage.

Difficult words

  • phage — a tiny virus that attacks bacteria
  • genome — all the genetic instructions of a living thing
    genomes
  • gene — a small part of genetic material giving instructions
    genes
  • synthetic — made by people, not made by nature
  • bacterial — related to bacteria, small living cells
  • infection — when bacteria or other germs cause illness
    infections

Tip: hover, focus or tap highlighted words in the article to see quick definitions while you read or listen.

Discussion questions

  • Have you heard the word phage before?
  • Do you know what DNA does?
  • Would you like to learn more about genes?

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