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New drug pair helps fight rifampicin-resistant tuberculosis — Level B2 — a red brain with green and yellow lines
31 Dec 2025

New drug pair helps fight rifampicin-resistant tuberculosis

Scientists paired rifampicin with a probe called AAP-SO2 that binds bacterial RNA polymerase at a different site and slows transcription. The pair killed resistant mutants in culture and was especially effective in a rabbit model.

Photo by Giovanni Crisalfi, Unsplash

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