#Medicine56
New injection may help heart heal after a heart attack
Researchers developed a simple injection that makes muscle release a natural hormone called ANP. A study in Science found one dose produced the hormone for weeks and the treatment may help the heart recover after an attack.
Photo by David Trinks, Unsplash
Needle-free spray delivers last-resort antibiotics
Researchers developed a needle-free spray-mist device to push last-resort antibiotics through the skin into infected tissue. The method aims to treat drug-resistant infections while reducing organ damage linked to intravenous delivery.
New inhaled nanoparticle treatment for tuberculosis
Researchers at the University at Buffalo developed inhalable nanoparticles that carry rifampin to lung immune cells. In mice the treatment kept drug levels in the lung much longer and may allow weekly dosing with fewer side effects.
Blocking a key immune signal may prolong post-surgery pain
A study led by Geoffroy Laumet found that blocking the immune molecule TNF-α after surgery in mice made pain last longer. The authors warn this does not mean stopping all anti-inflammatory treatment and call for targeted approaches.
New modular CAR-T system controls where and when cells attack
Researchers at the University of Chicago created GA1CAR, a modular CAR-T system that uses short-lived Fab fragments to guide and pause tumor targeting. In animal tests the same cells were redirected to different tumors and remained functional.
New drug pair helps fight rifampicin-resistant tuberculosis
Scientists paired rifampicin with a probe called AAP-SO2 that binds bacterial RNA polymerase at a different site and slows transcription. The pair killed resistant mutants in culture and was especially effective in a rabbit model.