#Biology6
Atlas maps how aging reshapes cells
Scientists at Rockefeller University profiled nearly 7 million cells from 21 organs in mice at three ages. The atlas reveals cell-type shifts, coordinated changes across organs, strong sex differences and genomic sites linked to immunity.
Photo by The New York Public Library, Unsplash
Brown study suggests targeting mTORC2 could help fight cancer
Researchers at Brown University report that blocking the mTORC2 protein complex, while leaving mTORC1 active, may stop cancer growth signals without triggering survival pathways. The work offers a new direction for designing cancer drugs.
Mechanical tipping point behind sudden fibrosis
Scientists found a mechanical "tipping point" that makes groups of cells switch quickly from healthy to fibrotic states. Collagen fibers, cell spacing and crosslinking control this abrupt change and affect how far mechanical signals travel.
Alternative splicing linked to mammal lifespan
A study in Nature Communications compared alternative splicing across 26 mammal species (lifespans 2.2–37 years) and found splicing patterns better predict maximum lifespan than gene activity; the brain shows many lifespan-linked events controlled by RNA-binding proteins.
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