All stories — Page 26
Biosensor reveals cancer-specific vulnerability in PRMT5
Researchers found that a metabolite change in some tumors makes the protein PRMT5 bind MTA instead of SAM. A new NanoBRET biosensor and a probe called CBH-002 measure drug binding to this cancer-specific form of PRMT5 in live cells.
Lower chemotherapy dose helps people 80+ with lymphoma
A study found that people aged 80 and older with a common lymphoma often do better with a lower chemotherapy dose. Researchers used data from community cancer clinics and say the smaller dose kept effectiveness while reducing side effects.
Shared social media and changing networks in rural families
A study of rural students and one of their parents finds that university often increases who young people meet, while social media usually broadens networks. Sharing platforms between parents and children has mixed effects on network diversity and tolerance.
Light tool measures activity inside living brain cells
Researchers developed a bioluminescent calcium sensor called CaBLAM to record activity inside living brain cells without external light. The tool works in mice and zebrafish and enables long recordings that avoid damage from bright light.
Some low-cost glucometers read newborn glucose accurately
A Rice360 study tested commonly available point-of-care glucometers in the lab to see if low-cost models can measure newborn glucose safely. Several inexpensive meters gave reliable readings at neonatal ranges, offering options for low-resource hospitals.
AI tool helps local autism diagnosis in Missouri
Researchers at the University of Missouri tested the FDA-approved CanvasDx, an AI device, to help primary care evaluate autism where specialty centres are far away. In a study it gave determinate results for 52% of 80 children and matched clinicians' diagnoses.
Most young users still smoke nicotine, tobacco or cannabis
A 2022–23 study of people aged 12–34 found most young Americans who use nicotine, tobacco or cannabis still smoke one or more combustible products. The research groups users by their usual product patterns and urges targeted prevention.