- Cancer cells can change how a protein works.
- The protein is called PRMT5 and acts in genes.
- In some tumors PRMT5 binds a cancer molecule.
- This binding is different from normal cells.
- Scientists made a small sensor for live cells.
- The sensor shows when drugs reach PRMT5.
- The test helps find drugs that spare normal cells.
- Many universities and funders supported the research.
- This idea could make cancer drugs safer.
- Researchers measured drug binding inside living cells.
Difficult words
- protein — A molecule in cells that does many jobs
- gene — A piece of DNA that holds instructionsgenes
- tumor — A group of abnormal cells that may growtumors
- bind — To attach firmly to another molecule or partbinds, binding
- sensor — A small device that detects and shows signals
- drug — A chemical used to treat or affect illnessdrugs
Tip: hover, focus or tap highlighted words in the article to see quick definitions while you read or listen.
Discussion questions
- Do you think safer cancer drugs are important?
- Have you ever had a medical test?
- Would you like medicines that do not hurt normal cells?
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