#Cancer16
AI helps detect melanoma from skin images
Researchers at the University of Missouri tested artificial intelligence to help detect melanoma from images of skin. They trained models on many pictures and found combined models improved accuracy, aiming to support faster care.
Photo by Joshua van der Schyff, Unsplash
New modular CAR-T system controls where and when cells attack
Researchers at the University of Chicago created GA1CAR, a modular CAR-T system that uses short-lived Fab fragments to guide and pause tumor targeting. In animal tests the same cells were redirected to different tumors and remained functional.
Clock disruption speeds breast cancer in models
New research finds that repeating disruption of the body’s 24-hour clock changes breast tissue, weakens immune defenses and leads to faster, more aggressive breast cancer in experimental models. The study links altered light–dark schedules to worse outcomes.
Biosensor reveals cancer-specific vulnerability in PRMT5
Researchers found that a metabolite change in some tumors makes the protein PRMT5 bind MTA instead of SAM. A new NanoBRET biosensor and a probe called CBH-002 measure drug binding to this cancer-specific form of PRMT5 in live cells.
Lower chemotherapy dose helps people 80+ with lymphoma
A study found that people aged 80 and older with a common lymphoma often do better with a lower chemotherapy dose. Researchers used data from community cancer clinics and say the smaller dose kept effectiveness while reducing side effects.
Brown study suggests targeting mTORC2 could help fight cancer
Researchers at Brown University report that blocking the mTORC2 protein complex, while leaving mTORC1 active, may stop cancer growth signals without triggering survival pathways. The work offers a new direction for designing cancer drugs.
Virtual diet and exercise program helps people with lymphoma
A study tested a virtual diet and exercise program for people getting chemotherapy for lymphoma. The program improved symptoms, attendance was high, and participants had better strength and physical performance during treatment.