Scientists found that older, weaker muscle releases fewer extracellular vesicles and less of a microRNA called miR-7a-5p. Exercise can restore vesicle release and may help reduce cancer risk in older adults. The work suggests new biomarkers and therapies.
Photo by julien Tromeur, Unsplash
A phase 1 trial found the personalized DNA vaccine GNOS-PV01 is safe and shows early signs of activity against glioblastoma. The small study at Siteman Cancer Center and WashU Medicine reported immune responses and encouraging clinical outcomes.
Researchers developed a genetically encoded protein sensor, called MAPPER, that makes molecular activity visible to MRI by changing water movement in cells. The modular system could let scientists image processes like cancer and inflammation continuously in animals.
New research finds that some chemotherapy agents can make cancer cells behave like virus‑infected cells. This viral mimicry activates the innate immune system and could let doctors use lower drug doses with better results.
Researchers tested a home exercise program during chemotherapy and found patients who followed it kept daily activity and reported clearer thinking. The trial compared a six-week exercise plan with standard care during treatment.
Researchers report a modified oral vaccine made from Listeria that primes immune cells in the gut and limits tumor growth in mice. The vaccine worked best when combined with immune checkpoint inhibitors and caused few side effects.
