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New enzyme from neurons can turn on pain after injury — Level A1 — white mouse lot toy

New enzyme from neurons can turn on pain after injuryCEFR A1

15 Dec 2025

Adapted from Stacey Plaisance-Tulane, Futurity CC BY 4.0

Photo by James Wainscoat, Unsplash

Level A1 – Beginner
2 min
70 words
  • Scientists discovered a new way that neurons switch on pain.
  • This change happens after an injury to the body.
  • Active neurons release a signal outside the cell.
  • The signal makes nearby cells send pain messages.
  • In mice, extra signal made pain responses stronger.
  • When researchers removed the signal, mice felt less pain.
  • The mice still moved and sensed normally after removal.
  • The discovery could help safer pain medicines in future.

Difficult words

  • neuroncell that sends messages in the body
    neurons
  • signala message sent from one cell to another
  • injuryharm to the body or a body part
  • releaseto let something go out from a cell
  • removeto take something away or out
    removed
  • discoveryfinding something new that we did not know

Tip: hover, focus or tap highlighted words in the article to see quick definitions while you read or listen.

Discussion questions

  • Have you felt more pain after an injury?
  • Do you use medicine when you have pain?
  • Do you think this discovery can help people?

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