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Genes linked to chronic kidney disease (Level A1) — orange pomelo on gray surface

Genes linked to chronic kidney diseaseCEFR A1

5 Dec 2025

LevelA1
A2
B1
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Adapted from Rochita Ghosh-U. Missouri, Futurity • CC BY 4.0

Photo by charlesdeluvio, Unsplash

Level A1 – Beginner
2 min
72 words
  • Chronic kidney disease affects many adults.
  • About 36 million adults have the condition.
  • Many adults do not know they have CKD.
  • CKD can lead to dialysis or kidney transplant.
  • Kidneys lose small blood vessels and get inflamed.
  • Fibrosis means scar tissue replaces normal kidney tissue.
  • Alejandro Chade leads the research team.
  • Silencing one gene reduces fibrosis in models.
  • The team plans to study genes in other tissues.
  • The research appears in Kidney360.

Difficult words

  • chronic — continuing for a long time
  • dialysis — a medical treatment to clean the blood
  • transplant — operation to move a healthy organ to someone
  • fibrosis — when scar tissue replaces normal tissue
  • inflamed — swollen and often red from injury or infection
  • gene — a small part of DNA that controls traits
    genes

Tip: hover, focus or tap highlighted words in the article to see quick definitions while you read or listen.

Discussion questions

  • Do you know anyone with kidney disease?
  • Have you heard of dialysis?
  • Would you like to learn about genes?

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