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Brain differences in WTC responders with PTSD — Level A2 — a black and white photo of various mri images

Brain differences in WTC responders with PTSDCEFR A2

28 Dec 2025

Adapted from Gregory Filiano-Stony Brook, Futurity CC BY 4.0

Photo by National Cancer Institute, Unsplash

Level A2 – High beginner / Elementary
2 min
116 words

Researchers studied long-term mental health in World Trade Center responders. Data from WTC health programs show about 23 percent of responders developed post-traumatic stress disorder (PTSD). Many still have symptoms years after the 2001 attacks.

The study used MRI scans and a measure called gray-white contrast (GWC). GWC looks at the border between gray matter and white matter in the cortex. In people with PTSD, gray matter appeared more like white matter. These differences were most linked to re-experiencing symptoms.

The team found that a clearer gray–white border looked healthy, while a less distinct border suggested abnormal myelin levels. Combining GWC with other health markers improved identification of responders with PTSD.

Difficult words

  • responderperson who helps or acts after an emergency
    responders
  • post-traumatic stress disorderlong mental health problem after a very bad event
    post-traumatic stress disorder (PTSD)
  • gray-white contrasthow different gray and white matter look
    gray-white contrast (GWC)
  • cortexouter part of the brain
  • myelinfatty layer around nerves that helps signals

Tip: hover, focus or tap highlighted words in the article to see quick definitions while you read or listen.

Discussion questions

  • How could having long-term symptoms affect a person's daily life?
  • Why is it helpful to use GWC together with other health markers?
  • Would you agree to get an MRI if a doctor recommended it? Why or why not?

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Brain differences in WTC responders with PTSD — English Level A2 | LingVo.club