Rapid diagnostic tests help treat malaria quickly, especially in remote places without labs. The World Health Organization says about 4 million people a year are affected by malaria in Southeast Asia. Researchers from the Shoklo Malaria Research Unit did a study on the Thailand–Myanmar border between October 2024 and January 2025. They compared Abbott-Bioline with another rapid test and with microscopy.
The SMRU team reported that Abbott-Bioline detected only 18% of Plasmodium falciparum infections and 44% of Plasmodium vivax infections confirmed by microscopy. Many positive cases made only a faint line on the device, even when patients had fever. The study authors said the test is "not fit for purpose" and called for its removal. Abbott said its review found the tests were "performing as intended" and a WHO-qualified lab confirmed the company findings. WHO has reviewed reports since August 2024 and issued a notice on 31 March 2025.
Difficult words
- malaria — a dangerous disease spread by mosquitoes.
- test — a method to check for something.
- diagnosing — finding out what is wrong with someone.
- recommend — to suggest someone do something.
- false-negative — not showing something is true when it is.
- researchers — people who study a topic to learn more.
- discover — to find out something new.discovered
Tip: hover, focus or tap highlighted words in the article to see quick definitions while you read or listen.
Discussion questions
- Why is it important to have accurate tests for diseases?
- How can false-negative results affect patients?
- What alternatives to the current test might work better?
Related articles
Targeting a brain circuit to reduce opioid relapse
Researchers at Washington State University found that lowering activity in a specific brain connection cut heroin-seeking in a preclinical model. The study identifies a pathway between the prelimbic cortex and the paraventricular thalamus and tests two ways to reduce its activity.
Mpox may be spreading quietly in Nigeria
A study in Nigeria tested archived blood from healthy adults and found signs of hidden mpox exposure. Some people had old smallpox antibodies and a small number showed recent immune responses without symptoms, suggesting low-level virus circulation.
