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Elite controllers: people who control HIV without medicine — Level A2 — pink and white flower petals

Elite controllers: people who control HIV without medicineCEFR A2

26 Sept 2024

Adapted from Elna Schütz, SciDev CC BY 2.0

Photo by CDC, Unsplash

Level A2 – High beginner / Elementary
2 min
80 words

About one in 200 people with HIV are elite controllers. They keep the virus at undetectable levels without antiretroviral therapy (ARVs). Having an undetectable viral load means there is not enough virus to pass to others.

Scientists, including Thumbi Ndung'u, study these people to find genetic traits and immune features. Research in African populations and a project called the HIV Host Genome project aim to find any distinct genes. Some elite controllers join studies and donate samples to help science.

Difficult words

  • elite controllerperson who keeps HIV at low viral levels
    elite controllers
  • undetectablevirus amount too low to be measured
  • antiretroviral therapymedicine treatment that stops HIV from growing
  • viral loadamount of virus in a person's blood
  • genetic traita feature that comes from a person's genes
    genetic traits
  • immune featurepart of the body's defence system
    immune features

Tip: hover, focus or tap highlighted words in the article to see quick definitions while you read or listen.

Discussion questions

  • Would you join a medical study and donate samples? Why or why not?
  • Why are scientists interested in people who keep the virus undetectable?
  • How would you explain 'undetectable viral load' to a friend?

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