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Antibody and EGFR–STAT1 pathway point to new fibrosis treatments — Level A1 — a close up of a red flower

Antibody and EGFR–STAT1 pathway point to new fibrosis treatmentsCEFR A1

25 Nov 2025

Adapted from Yale, Futurity CC BY 4.0

Photo by Ian Talmacs, Unsplash

Level A1 – Beginner
2 min
63 words
  • Fibrotic diseases make extra scar tissue.
  • They can harm organs and skin.
  • They often lower quality of life.
  • Fibrosis causes about 45% of deaths in developed nations.
  • Yale researchers studied a molecule called epiregulin.
  • An antibody can block epiregulin and EGFR.
  • They tested the antibody in mice and biopsies.
  • Blocking epiregulin reduced signs of fibrosis.
  • They found the protein STAT1 helps fibrosis start.

Difficult words

  • researchthe study of a subject to find new information.
    Researchers
  • diseasean illness that affects a person's health.
    diseases
  • scarringthe marks left on the body after healing.
  • antibodya substance made by the body to fight illness.
  • treatmentthe care given to improve health.
    treatments

Tip: hover, focus or tap highlighted words in the article to see quick definitions while you read or listen.

Discussion questions

  • What do you think about new treatments for diseases?
  • How do you feel about research in medicine?
  • Why is it important to study diseases?

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Antibody and EGFR–STAT1 pathway point to new fibrosis treatments — English Level A1 | LingVo.club