Researchers at University of Rochester Medicine report that antibiotics given to newborns can alter gut bacteria and reprogram lung immune cells in mice and humans. These changes can last into young adulthood and may affect breathing.
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Researchers report a vaccine approach using cell-derived extracellular vesicles that display inverted influenza hemagglutinin proteins. Tests in mice showed broad immune responses after intranasal dosing, suggesting potential for a universal mucosal flu vaccine.
New research finds that some chemotherapy agents can make cancer cells behave like virus‑infected cells. This viral mimicry activates the innate immune system and could let doctors use lower drug doses with better results.
Researchers report a modified oral vaccine made from Listeria that primes immune cells in the gut and limits tumor growth in mice. The vaccine worked best when combined with immune checkpoint inhibitors and caused few side effects.
A Washington State University study found that a lesser-known TWEAK–Fn14 pathway can join with TNF to increase inflammation. Blocking Fn14 reduced this surge and may explain why some patients do not respond to TNF inhibitors.
New research finds that repeating disruption of the body’s 24-hour clock changes breast tissue, weakens immune defenses and leads to faster, more aggressive breast cancer in experimental models. The study links altered light–dark schedules to worse outcomes.
A research team created changed antibodies that stop human cytomegalovirus from disabling immune responses. Lab tests show the antibodies reduce virus spread, but researchers say more testing is needed before they can be used in people.