Researchers at Yale found a human antibody that blocks epiregulin and lowers fibrosis markers. They also show EGFR activates STAT1 in fibroblasts, suggesting two treatment paths: block epiregulin or target the EGFR–STAT1 pathway.
Photo by Ian Talmacs, Unsplash
Researchers at the University of Utah found two different microglia types in the brain that can cause or prevent anxiety in mice. The work suggests new ways to think about treatments, but therapies are not near-term.
Researchers at the University of Pittsburgh made a wearable biosensor that detects antibodies in interstitial fluid in 10 minutes without a blood draw. The tiny carbon nanotube sensors are highly sensitive and the work appears in Analytical Chemistry.
Researchers report a biodegradable microneedle patch that delivers interleukin-4 to injured heart tissue. The local treatment encourages healing immune cells, reduces scarring, and may improve heart recovery while avoiding systemic side effects.
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