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New Malaria Drug Shows Promise Against Resistance — white and red plastic bottle

New Malaria Drug Shows Promise Against ResistanceCEFR B1

14 Nov 2025

Adapted from Ben Deighton, SciDev CC BY 2.0

Photo by Mufid Majnun, Unsplash

AI-assisted adaptation of the original article, simplified for language learners.

GanLum is a new malaria treatment that has shown significant promise in clinical trials. It uses a new molecule called ganaplacide. This molecule is different from any current malaria treatments, meaning the malaria parasite has not encountered it before. As a result, the drug can effectively treat patients, even those with drug-resistant malaria.

The trials involved over 1,600 patients across 12 countries in sub-Saharan Africa. GanLum proved to cure about 97.4% of patients, which is higher than existing treatments. Additionally, it targets malaria in a way that helps prevent transmission to mosquitoes, breaking the cycle of infection.

If regulatory approvals proceed smoothly, GanLum could be available for public use by 2027. This new treatment represents a hopeful advance against the growing threat of malaria drug resistance.

Difficult words

  • treatmentA way to help someone who is sick.
    treat, treatments
  • promiseA belief that something will be successful.
  • patientA person receiving medical care.
    patients
  • transmissionThe act of passing something on.
  • resistanceAbility to fight against something harmful.

Tip: hover, focus or tap highlighted words in the article to see quick definitions while you read or listen.

Discussion questions

  • What do you think about new malaria treatments?
  • How important is it to prevent disease transmission?
  • What challenges might GanLum face before it is approved?

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