- Some people have obsessive-compulsive disorder, called OCD.
- Scientists studied the brain in people with OCD.
- Participants did a sequence task in an MRI scanner.
- They named colors or shapes in a set order.
- People with OCD did the task as well.
- But their brains showed more activity than controls.
- Extra activity was in memory and vision areas.
- New brain targets could help future treatment.
- Researchers hope to improve brain stimulation methods.
- The study links experiments to daily decision making.
Difficult words
- obsessive-compulsive disorder — a mental illness with repeated unwanted thoughts
- participant — a person who takes part in a studyParticipants
- sequence — a set of things in a fixed order
- control — a group used to compare study resultscontrols
- activity — something the brain or body does
- treatment — health care to help a sick person
Tip: hover, focus or tap highlighted words in the article to see quick definitions while you read or listen.
Discussion questions
- Have you ever been in an MRI scanner?
- Do you make many decisions every day?
- Would you try a new treatment if it could help?
Related articles
Human intelligence arises from coordinated brain networks
Researchers used neuroimaging and two adult datasets to test the Network Neuroscience Theory. They found that general intelligence reflects system-level organization and coordination across large-scale brain networks, with implications for development, injury and artificial systems.
Nasal spray reverses signs of brain aging in models
Researchers developed a nasal spray that delivers extracellular vesicles with microRNAs to the brain. In preclinical models it reduced inflammation, restored neuronal mitochondria and improved memory, but human tests are still needed.
Protein sensor lets MRI detect molecular activity
Researchers developed a genetically encoded protein sensor, called MAPPER, that makes molecular activity visible to MRI by changing water movement in cells. The modular system could let scientists image processes like cancer and inflammation continuously in animals.
Brainstem and spinal cord help control hand movements
A UC Riverside-led study published in the Proceedings of the National Academy of Sciences found that voluntary hand signals travel through the brainstem and top spinal segments as well as directly from the cortex. Mapping this pathway could guide new stroke therapies.