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High-dose antioxidants may harm sperm and offspring — Level A2 — white mouse lot toy

High-dose antioxidants may harm sperm and offspringCEFR A2

16 Feb 2026

Adapted from Texas A&M University, Futurity CC BY 4.0

Photo by James Wainscoat, Unsplash

Level A2 – High beginner / Elementary
2 min
78 words

A study in mice tested two common antioxidants, including NAC and selenium. Male mice received the antioxidants for a period before they mated. Researchers expected the supplements to lower oxidative stress.

Instead, offspring of treated males showed different skull and face shapes. Female offspring had closer-set eyes and smaller skulls. The researchers say high, regular antioxidant doses can be unbalanced and may harm sperm. They recommend men planning children use caution and avoid very large supplement doses.

Difficult words

  • antioxidantsubstances that protect cells from damage
    antioxidants
  • oxidative stresscell damage caused by harmful oxygen molecules
  • offspringchildren or babies of an animal or person
  • spermmale reproductive cells that fertilize eggs
  • dosethe amount of a drug or supplement
    doses
  • recommendto tell people what is best to do

Tip: hover, focus or tap highlighted words in the article to see quick definitions while you read or listen.

Discussion questions

  • If you were planning a child, would you change your supplement use? Why or why not?
  • Do you think taking large doses of supplements is safe? Explain briefly.

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