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Brazil approves single-dose dengue vaccine — a computer screen with a number of cases on it

Brazil approves single-dose dengue vaccineCEFR A1

3 Dec 2025

Adapted from Rodrigo de Oliveira Andrade, SciDev CC BY 2.0

Photo by KOBU Agency, Unsplash

AI-assisted adaptation of the original article, simplified for language learners.

  • Butantan-DV is a dengue vaccine made in Brazil.
  • Anvisa approved it on 26 November.
  • It is for people aged 12 to 59 years.
  • The vaccine needs only one dose to work.
  • One dose can help reach remote Amazon communities.
  • Trials in Brazil had 16,000 volunteers over nearly a decade.
  • The vaccine showed 74.7% overall and 91.6% severe efficacy.
  • More than 1,000,000 doses are ready for distribution.
  • It will join the national programme in early 2026.

Difficult words

  • vaccinemedicine that helps the body avoid disease
  • approvedto say yes to a new medicine
  • dosesmall amount of medicine for one time
    doses
  • remotefar away from towns and cities
  • Trialsstudy to test a medicine or vaccine
  • volunteersperson who joins a study by choice
  • efficacyhow well a medicine or vaccine works

Tip: hover, focus or tap highlighted words in the article to see quick definitions while you read or listen.

Discussion questions

  • Would you take a vaccine that needs one dose?
  • Have you visited a remote area?

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