Researchers report a vaccine approach using cell-derived extracellular vesicles that display inverted influenza hemagglutinin proteins. Tests in mice showed broad immune responses after intranasal dosing, suggesting potential for a universal mucosal flu vaccine.
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Researchers report a modified oral vaccine made from Listeria that primes immune cells in the gut and limits tumor growth in mice. The vaccine worked best when combined with immune checkpoint inhibitors and caused few side effects.
Gagandeep Kang, a leading expert on enteric diseases, urges India to prepare tools to prevent viral outbreaks. She helped develop indigenous rotavirus vaccines, built surveillance networks and now works at the Gates Foundation.
A new mouse study reports an experimental vaccine that produced rapid protection and antibodies that lasted up to 18 months. Researchers say a booster strengthened and extended immune responses and plan manufacturing steps before human trials.
Emory University measured antibody responses in 24 people after the 2023–24 monovalent vaccine targeting Omicron XBB.1.5. The study found long-lasting antibodies, cross-reactive protection with the ancestral WA1 strain, and a 2.8-fold boost from immune imprinting.
A study in Science Advances finds that offering RSV immunizations year‑round would lower the chance of large seasonal outbreaks in the United States. Researchers compared spread in cities and rural areas and tested seasonal versus year‑round schedules.
Cholera spread widely in 2024, with 560,823 reported cases and 6,028 deaths. Conflict, climate shocks and damaged water and health services drove outbreaks, while vaccines and better water and sanitation are key to preventing deaths.
