#Vaccines19
Ebola outbreak in DRC pushes vaccine effort
WHO declared the Ebola outbreak centred in the Democratic Republic of Congo a public health emergency. International groups are funding vaccine and treatment work, but response teams say efforts are struggling to keep up.
Photo by Kingsley Hemans, Unsplash
New mucosal EV vaccine with inverted HA may protect against many flu strains
Researchers report a vaccine approach using cell-derived extracellular vesicles that display inverted influenza hemagglutinin proteins. Tests in mice showed broad immune responses after intranasal dosing, suggesting potential for a universal mucosal flu vaccine.
New oral Listeria vaccine shows promise against colorectal cancer
Researchers report a modified oral vaccine made from Listeria that primes immune cells in the gut and limits tumor growth in mice. The vaccine worked best when combined with immune checkpoint inhibitors and caused few side effects.
Gagandeep Kang on Vaccines, Surveillance and Child Health in India
Gagandeep Kang, a leading expert on enteric diseases, urges India to prepare tools to prevent viral outbreaks. She helped develop indigenous rotavirus vaccines, built surveillance networks and now works at the Gates Foundation.
Experimental vaccine gives lasting protection in mice against CCHF
A new mouse study reports an experimental vaccine that produced rapid protection and antibodies that lasted up to 18 months. Researchers say a booster strengthened and extended immune responses and plan manufacturing steps before human trials.