Researchers at two California universities reviewed pivotal clinical trials done between 2017 and 2023. They found that only a small share of trials used to approve new drugs reflect the United States racial and ethnic makeup. Enrollment of Black and Hispanic people fell from 2021, while Asian participation rose and white participation stayed mainly steady.
The study notes many trials follow International Council for Harmonisation standards and take place in a few regions. It says much of Africa and large parts of Latin America are rarely included. The authors recommend setting diversity goals early, choosing testing locations to match local needs, and collecting biological samples to study drug responses.
Difficult words
- trial — a medical study to test a medicineclinical trials, trials
- enrollment — the act of people joining a study
- diversity — the presence of many different kinds of peoplediversity goals
- region — a large area of a country or worldregions
- sample — a small biological part taken for studybiological samples
- approve — to officially allow or accept something
Tip: hover, focus or tap highlighted words in the article to see quick definitions while you read or listen.
Discussion questions
- Why is it important for drug trials to include people from different racial and ethnic groups?
- What can researchers do to include people from Africa or Latin America?
- Would you join a clinical trial? Why or why not?
Related articles
Needle-free spray delivers last-resort antibiotics
Researchers developed a needle-free spray-mist device to push last-resort antibiotics through the skin into infected tissue. The method aims to treat drug-resistant infections while reducing organ damage linked to intravenous delivery.
Lower chemotherapy dose helps people 80+ with lymphoma
A study found that people aged 80 and older with a common lymphoma often do better with a lower chemotherapy dose. Researchers used data from community cancer clinics and say the smaller dose kept effectiveness while reducing side effects.
Dementia rising in Africa as researchers seek answers
Dementia is increasing in Africa as populations age. Research and evidence in the region are limited, so scientists study genetics, new detection tools and community measures while working with traditional healers to reduce stigma.
Gene Variant Raises Heart Failure Risk After Myocarditis in Children
A study found that a cardiomyopathy gene variant is more common in children who develop dilated cardiomyopathy after myocarditis. Researchers describe a "double hit" model and advise genetic testing to identify higher risk.