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Engineered bacteria produce tagatose sweetener — Level A2 — a group of yellow balls sitting on top of a blue substance

Engineered bacteria produce tagatose sweetenerCEFR A2

22 Dec 2025

Level A2 – High beginner / Elementary
2 min
112 words

Tagatose is a rare sugar that tastes like sugar but has fewer calories. It appears in very small amounts in milk and some fruits, so it is usually manufactured rather than extracted.

Scientists at a university engineered the bacterium Escherichia coli to make tagatose from common glucose. They added a slime mold enzyme called Gal1P and another enzyme named arabinose isomerase to complete the conversion. The bacterial process gives higher yields than older methods.

The US Food and Drug Administration calls tagatose generally safe. Because it is only partly absorbed and much is fermented by gut bacteria, clinical studies show only small rises in blood sugar and insulin after people eat it.

Difficult words

  • tagatosea rare sweet molecule with fewer calories
  • manufactureto make a product in large amounts
    manufactured
  • engineerto change something using scientific methods
    engineered
  • enzymea protein that speeds up chemical reactions
  • bacteriuma very small living cell, often single-celled
  • fermentto change food using bacteria or yeast
    fermented

Tip: hover, focus or tap highlighted words in the article to see quick definitions while you read or listen.

Discussion questions

  • Would you try a sweetener that has fewer calories like tagatose? Why or why not?
  • The article says tagatose appears in milk and some fruits. Which foods do you eat that might contain small amounts of it?
  • The scientists used bacteria and enzymes to make tagatose. How do you feel about foods made with bacteria or enzymes?

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