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Calorie restriction improves muscle insulin response in old rats — Level A1 — A white hamster sitting on a table next to a plate of food

Calorie restriction improves muscle insulin response in old ratsCEFR A1

28 Nov 2025

Level A1 – Beginner
2 min
79 words
  • Rats in the study were 24 months old.
  • They ate 35% less food each day.
  • The calorie change lasted for eight weeks.
  • Scientists measured protein phosphorylation and metabolites in muscle.
  • The study found proteins Lmod1 and Ehbp1l1 linked to blood sugar.
  • Calorie restriction changed many muscle proteins a lot.
  • Insulin helped muscles take up more sugar.
  • Females had greater glucose uptake than males.
  • The team measured about 1,000 metabolites in total.
  • Around 40% of those metabolites changed with diet.

Difficult words

  • researchStudy to find new information or facts.
  • muscleTissue in the body that helps with movement.
    muscles
  • sugarA sweet substance often used in food.
  • proteinSubstance in food important for the body.
    proteins
  • diabetesA disease that affects how the body uses sugar.

Tip: hover, focus or tap highlighted words in the article to see quick definitions while you read or listen.

Discussion questions

  • How do you think eating less food affects you?
  • Why is it important to understand how muscles change?
  • Have you heard about diabetes before?

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Calorie restriction improves muscle insulin response in old rats — English Level A1 | LingVo.club