#Virology7
Brain prepares for viral attack within hours of distant infection
Researchers at Rockefeller University found that the brain begins an antiviral response within hours after an infection far from the head. Mouse experiments showed signals from infected tissue activate genes in the brain and that early priming can improve survival.
Photo by National Institute of Allergy and Infectious Diseases, Unsplash
New Oral Drug Candidate for Measles and Parainfluenza
Researchers identified a clinical candidate called GHP-88310 that inhibits orthoparamyxoviruses and tested it in animal models and human airway cultures. The compound showed broad once-daily oral activity and good tolerance in animals.
Experimental vaccine gives lasting protection in mice against CCHF
A new mouse study reports an experimental vaccine that produced rapid protection and antibodies that lasted up to 18 months. Researchers say a booster strengthened and extended immune responses and plan manufacturing steps before human trials.
Milk glands in many mammals have receptors for H5N1
A study found that milk gland tissue from pigs, sheep, goats, beef cattle, alpacas and humans contains sialic acid receptors that can let H5N1 attach to cells. Researchers warn of surveillance and concerns about raw milk from mammals.
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