#Immunotherapy7

28 May 2026

Personalized DNA vaccine shows promise against glioblastoma

A phase 1 trial found the personalized DNA vaccine GNOS-PV01 is safe and shows early signs of activity against glioblastoma. The small study at Siteman Cancer Center and WashU Medicine reported immune responses and encouraging clinical outcomes.

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Photo by CDC, Unsplash

30 Apr 2026

Gene Dec2 helps pancreatic cancer hide from immune cells

Researchers found that the gene Dec2 can disguise pancreatic cancer cells and that Dec2 levels change during the day. The study may help improve immunotherapy, vaccines and new treatment timing for this disease.

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27 Feb 2026

Common medicines can change immunotherapy

Researchers say everyday prescription and over‑the‑counter medicines may change how well cancer immunotherapy works. They call for better recording of all medicines and more studies to confirm these effects.

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31 Dec 2025

New modular CAR-T system controls where and when cells attack

Researchers at the University of Chicago created GA1CAR, a modular CAR-T system that uses short-lived Fab fragments to guide and pause tumor targeting. In animal tests the same cells were redirected to different tumors and remained functional.

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29 Dec 2025

How the T cell receptor starts immune attacks

Scientists used cryo-EM and membrane-like nanodiscs to image the T cell receptor. They found it rests closed and opens when it meets a target antigen, a result that may help improve immunotherapies.

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10 Dec 2025

Antibody therapy clears traces of multiple myeloma

A phase 2 trial found that an antibody drug, linvoseltamab, removed detectable disease in patients with multiple myeloma using very sensitive bone marrow tests. Researchers report acceptable safety and will expand the trial.

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25 Nov 2025

Nasal nanomedicine clears deadly brain tumours in mice

Researchers used spherical nucleic acids given through the nose to deliver a STING-activating therapy that eradicated glioblastoma in mice and produced long-term immunity. The study appears in PNAS.

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